REDISSEC

• Cardiovascular risk in subjects over 55 years of age and cognitive performance after five years. NEDICES2-RISK study. Study protocol 28 noviembre 2022
  BACKGROUND: Cognitive impairment and dementia have a high prevalence among the elderly and cause significant socio-economic impact. Any progress in their prevention can benefit millions of people. Current data indicate that cardiovascular risk (CVR) factors increase the risk of developing cognitive impairment and dementia. Using models to calculate CVR specific for the Spanish population can […]
  Ester Tapias-Merino
• Aetiological and prognostic roles of frailty, multimorbidity and socioeconomic characteristics in the development of SARS-CoV-2 health outcomes: protocol for systematic reviews of population-based studies 22 noviembre 2022
  INTRODUCTION: There is growing evidence that the impact of COVID-19 crisis may be stronger for individuals with multimorbidity, frailty and lower socioeconomic status. Existing reviews focus on few, mainly short-term effects of COVID-19 illness and patients with single chronic disease. Information is also largely missing for population representative samples.Applying population-based approach, the systematic reviews will […]
  Tatjana T Makovski
• Diagnostic stability in substance-induced psychosis 18 noviembre 2022
  CONCLUSIONS: In interventions in episodes of SIP we must bear in mind that a significant proportion will progress to an SMD in the first three years.
  Lucía Inchausti
• Molecular Biomarkers for the Detection of Clinically Significant Prostate Cancer: A Systematic Review and Meta-analysis 17 noviembre 2022
  CONCLUSIONS: The PHI test has a high diagnostic accuracy rate for csPCa detection, and its incorporation in the diagnostic process could reduce unnecessary biopsies. However, there is a lack of evidence on patient-important outcomes and thus more research is needed.
  Tasmania Del Pino-Sedeño
• Use of health care services according to functional performance in community-dwelling older adults in Spain. An approach using GAMLSS models 17 noviembre 2022
  Functional performance in older adults is a predictor of survival and other health outcomes and its measurement is highly recommended in primary care settings. Functional performance and frailty are closely related concepts, and frailty status is associated with the use of health care services. However, there is insufficient evidence on the utilization of services profile […]
  Maider Mateo-Abad
• Facilitation as a component of evidence implementation: a multinational perspective 14 noviembre 2022
  CONCLUSION: The cases emphasized the complex nature of facilitation as a strategy for evidence implementation, indicating that contextual attributes and features define the range of knowledge, skills, and activities that should take place in order for facilitation to be effective. Although there appears to be some core components, tailoring and adaptation of the facilitation process […]
  Lucylynn Lizarondo
• Comorbidity Patterns in Patients with Atopic Dermatitis Using Network Analysis in the EpiChron Study 11 noviembre 2022
  CONCLUSIONS: Our study revealed the presence of different clinically meaningful comorbidity patterns in patients with AD. Our results can help to identify which comorbidities deserve special attention in these types of patients and to better understand the physio-pathological mechanisms underlying the disease associations identified. Further studies are encouraged to validate the results obtained in different […]
  Manuel Almenara-Blasco
• Diagnostic performance of machine learning models using cell population data for the detection of sepsis: a comparative study 9 noviembre 2022
  CONCLUSIONS: The best performance in the early detection of sepsis was achieved using the ML and AI models. However, external validation studies are needed to strengthen model derivation and procedure updating.
  Urko Aguirre
• Cost-effectiveness and epidemiological impact of gender-neutral HPV vaccination in Spain 8 noviembre 2022
  All EU countries have introduced Human papilloma virus (HPV) vaccination for adolescent girls and many countries are expanding the strategy to include adolescent boys. There is uncertainty about the cost-effectiveness and epidemiological impact of a gender-neutral HPV vaccination strategy. Here we present the results of an economic model adapted for Spain. Five vaccination strategies were […]
  Renata Linertová
• Laboratory protocol for the digital multiplexed gene expression analysis of nasopharyngeal swab samples using the NanoString nCounter system 7 noviembre 2022
  This paper describes a laboratory protocol to perform the NanoString nCounter Gene Expression Assay from nasopharyngeal swab samples. It is urgently necessary to identify factors related to severe symptoms of respiratory infectious diseases, such as COVID-19, in order to assess the possibility of establishing preventive or preliminary therapeutic measures and to plan the services to […]
  Marilina García Aranda
• Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses 31 octubre 2022
  CONCLUSIONS: In people without manifest cardiovascular disease or diabetes, mild-to-moderate kidney dysfunction is causally related to risk of CHD, highlighting the potential value of preventive approaches that preserve and modulate kidney function.
  Liam Gaziano
• Maternal Mortality in Africa: Regional Trends (2000-2017) 27 octubre 2022
  CONCLUSIONS: Maternal mortality has decreased in Africa, especially in the South African region. The only region close to the United Nations' target is the North African region. The remaining Sub-Saharan African regions are still far from achieving the goals. The West African region needs more extraordinary efforts to achieve the goals of the United Nations. […]
  Luc Onambele
• Estimation of the epidemiology of dementia and associated neuropsychiatric symptoms by applying machine learning to real-world data 22 octubre 2022
  CONCLUSIONS: The stigmatization factor conditions the social and attitudinal environment, delaying the diagnosis of dementia, preventing patients from receiving adequate care and exacerbating families' suffering. This study evidences the synergy between big data and real-world data for psychiatric epidemiological research.
  Javier Mar
• Factors associated with the hospital at home workload: A Delphi consensus study 22 octubre 2022
  CONCLUSIONS: The identified factors could serve for improving the organization and optimize the daily word of the HaH professionals.
  K Vrotsou
• Telemedicine for neurological diseases: A systematic review and meta-analysis 18 octubre 2022
  CONCLUSIONS: Well-designed and executed RCTs are needed to confirm our findings on stroke and to have more scientific evidence available for the other neurological diseases.
  Beatriz León-Salas