REDISSEC

• Impact of hypertension diagnosis on morbidity and mortality: a retrospective cohort study in primary care 24 marzo 2023
  CONCLUSION: The diagnosis of hypertension in the community environment, in patients without evidence of previous kidney or CV disease, is associated with a large increase in the risk of K/CVEs, but especially in individuals diagnosed before the age of 55. This diagnosis is only associated with an increase in kidney or cardiovascular mortality or overall […]
  Jesus Martín-Fernández
• Potency assessment of IFNγ-producing SARS-CoV-2-specific T cells from COVID-19 convalescent subjects 20 marzo 2023
  The development of new therapies for COVID-19 high-risk patients remains necessary to prevent additional deaths. Here, we studied the phenotypical and functional characteristics of IFN-γ producing-SARS-CoV-2-specific T cells (SC2-STs), obtained from 12 COVID-19 convalescent donors, to determine their potency as an off-the-shelf T cell therapy product. We found that these cells present mainly an effector […]
  Rubén Gil-Bescós
• Ultrasound assessment of diaphragmatic dynamics in patients with chronic obstructive pulmonary disease after treatment with indacaterol/glycopyrronium 17 marzo 2023
  CONCLUSIONS: Treatment with indacaterol/glycopyrronium 85/43 mcg every 24 hours for 3 months improved diaphragmatic mobility in patients with COPD with moderate to very severe airway obstruction. CU may be useful for assessing the response to treatment in these patients.
  A L Wangüemert-Pérez
• Clinical prediction rules for adverse evolution in patients with COVID-19 by the Omicron variant 15 marzo 2023
  CONCLUSIONS: We propose risk scales, based on basic information, easily-calculable, high-predictive that also function with the current Omicron variant and may help manage such patients in primary, emergency, and hospital care.
  Janire Portuondo-Jiménez
• Preventive behavior against SARS-CoV-2 infection in adults according to whether or not they live with children. A combined analysis of the nationwide COSMO-SPAIN and ENE-COVID surveys 13 marzo 2023
  INTRODUCTION: The protection of children is a major driver of behavior among those in charge of their care. We evaluated whether compliance with preventive measures against SARS-CoV-2 infection among adults living with children was different from that of those not living with them, in 2020.
  Imane Jroundi
• Five-year follow-up mortality prognostic index for colorectal patients 9 marzo 2023
  CONCLUSIONS: These results allow preventive and controlling measures to be established on long-term follow-up of these patients, based on a few easily measurable variables.
  Miren Orive
• Cost-effectiveness of universal childhood vaccination against hepatitis A in Spain: a dynamic approach 3 marzo 2023
  CONCLUSIONS: Universal infant vaccination strategy against hepatitis A would not be a cost-effective option from the NHS perspective in Spain.
  Cristina Valcárcel-Nazco
• "Geographical distribution of risk genotypes in pediatric patients with celiac disease in Spain" 1 marzo 2023
  Celiac disease is strongly associated with HLA DQ, specifically with haplotypes. DRB1*03-DQA1*05:01/DQB1*02:01 (DQ2.5),DRB1*07-DQA1*02:01/DQB1*02:02 (DQ2.2), DRB1*11-DQA1*05:05/DQB1*03:01 (DQ7.5), and DRB1*04-DQA1*03:01/DQB1*03:02 (DQ8). The distribution of these risk haplotypes in patients with celiac disease is different in the geographical areas investigated. A high frequency of DRB1*07- DQA1*02:01/DQB1*02:02 (DQ2.2) and DRB1*11-DQA1*05:05/DQB1*03:01 (DQ7.5), has been described in Southern...
  Félix Sánchez-Valverde
• Assessment of the Effectiveness, Socio-Economic Impact and Implementation of a Digital Solution for Patients with Advanced Chronic Diseases: The ADLIFE Study Protocol 25 febrero 2023
  Due to population ageing and medical advances, people with advanced chronic diseases (ACD) live longer. Such patients are even more likely to face either temporary or permanent reduced functional reserve, which typically further increases their healthcare resource use and the burden of care on their caregiver(s). Accordingly, these patients and their caregiver(s) may benefit from […]
  Borja García-Lorenzo
• Sex Differences in Multimorbidity, Inappropriate Medication and Adverse Outcomes of Inpatient Care: MoPIM Cohort Study 25 febrero 2023
  There is no published evidence on the possible differences in multimorbidity, inappropriate prescribing, and adverse outcomes of care, simultaneously, from a sex perspective in older patients. We aimed to identify those possible differences in patients hospitalized because of a chronic disease exacerbation. A multicenter, prospective cohort study of 740 older hospitalized patients (≥65 years) was […]
  Marisa Baré
• Diet Quality Changes by Educational Level among Adults in Spain from 2017 to 2021 25 febrero 2023
  Despite increasing attention on addressing socioeconomic disparities in diet quality, longitudinal studies are scarce. Furthermore, the effects of the COVID-19 pandemic on diet-related outcomes are yet to be fully understood. We examined changes in diet quality by educational level among adults in Madrid, Spain. We used data from recruitment (in 2017) and from 2021. At […]
  Isabel Romero
• A cross-sectional analysis identified co-authorship networks and scientific collaboration on reporting guidelines for health research 23 febrero 2023
  CONCLUSION: Our analysis identified key actors producing reporting guidelines, most intense collaborations, and 'citation classics' in the field. These results could potentially be used to strengthen collaborations for developing and disseminating reporting guidelines for health research.
  Ferrán Catalá-López
• Trends in hospitalization for urinary tract infection in the paediatric age group in the 2000-2015 period in Spain 22 febrero 2023
  CONCLUSIONS: The rate of hospitalization related to UTI in Spain in patients aged up to 14 years decreased during the 2000-2015 period. The highest hospitalization rates occurred in female patients and in the 0-to-1 year age group.
  Jesús Redondo Sánchez
• Characteristics of medical deserts and approaches to mitigate them: a scoping review 21 febrero 2023
  INTRODUCTION: Medical deserts are increasingly considered problematic and many countries employ a multitude of actions and initiatives to achieve a better distribution of the health workforce (HWF). This study systematically maps research and provides an overview of the definitions/characteristics of medical deserts. It also identifies contributing factors and approaches to mitigate medical deserts.
  Laura Seils
• Multimorbidity, social determinants and intersectionality in chronic patients. Results from the EpiChron Cohort 9 febrero 2023
  CONCLUSIONS: Our intersectional approach uncovered the large differences in the prevalence of multimorbidity that arise due to the synergies between the different socioeconomic and demographic exposures, beyond their expected additive effects.
  Aida Moreno-Juste