REDISSEC

• Drug interactions detected by a computer-assisted prescription system in primary care patients in Spain: MULTIPAP study 13 mayo 2021
  CONCLUSION: Drug interactions are prevalent in patients aged 65-74 years with multimorbidity and polypharmacy. The clinically relevant DDI frequency is low. The number of prescriptions taken is the most relevant factor associated with presenting a clinically relevant DDI.
  Eloísa Rogero-Blanco
• Cost-sharing increase, medication adherence and hospitalizations in schizophrenia patients: a natural experiment 11 mayo 2021
  Increases in medication cost-sharing rates remain a controversial system-wide cost-containment measure for chronic mental health patients. The objective was to investigate the effects of cost-sharing increases on adherence to prescribed antipsychotic medication and psychiatric hospitalizations among schizophrenia patients. In July 2012, a Spanish National Law raised the cost-sharing rate from 0 to 10% for pensioner […]
  Miquel Serra-Burriel
• Are We Improving? Update and Critical Appraisal of the Reporting of Decision Process and Quality Measures in Trials Evaluating Patient Decision Aids 10 mayo 2021
  CONCLUSION: There continues to be very little reported about the development or performance of measures used to evaluate the effectiveness of PtDAs in published trials. Minimum reporting standards have been published, and efforts to require investigators to use them are needed.
  Logan Trenaman
• Ozone therapy versus surgery for lumbar disc herniation: A randomized double-blind controlled trial 8 mayo 2021
  CONCLUSIONS: Our truncated trial showed that intradiscal ozone infiltrations decreased the requirements for conventional surgery, resulting in decreased hospitalization durations and associated costs. These findings and their magnitude are of interest to patients and health services providers. Further validation is ongoing.
  Bernardino Clavo
• Risk aversion, trust in institutions and contingent valuation of healthcare services: trying to explain the WTA-WTP gap in the Dutch population 6 mayo 2021
  CONCLUSIONS: Known differences between the perceived value of health services from the perspective of gains and losses could be related to people's characteristics. Trust in government but not aversion to risk was related to the WTA-WTP differences. Identifying a profile of citizens who are averse to losing health services should be considered when designing and […]
  Jesús Martín-Fernández
• Predictors of patient safety culture in hospitals in Venezuela: A cross-sectional study 5 mayo 2021
  An organization's culture with regard to patient safety is important because it defines the beliefs and practices of the organization, and consequently its efficiency and productivity.Knowing the level of this and the factors that influence or not their dynamic represents a challenge, due to the degree of complexity and specificity of the elements involved.The aim […]
  Mónica Susana Chirinos Muñoz
• Postlaunch evidence-generation studies for medical devices in Spain: the RedETS approach to integrate real-world evidence into decision making 4 mayo 2021
  The Monitoring Studies (MS) program, the approach developed by RedETS to generate postlaunch real-world evidence (RWE), is intended to complement and enhance the conventional health technology assessment process to support health policy decision making in Spain, besides informing other interested stakeholders, including clinicians and patients. The MS program is focused on specific uncertainties about the […]
  Pedro Serrano-Aguilar
• Changes in Multimorbidity and Polypharmacy Patterns in Young and Adult Population over a 4-Year Period: A 2011-2015 Comparison Using Real-World Data 30 abril 2021
  The pressing problem of multimorbidity and polypharmacy is aggravated by the lack of specific care models for this population. We aimed to investigate the evolution of multimorbidity and polypharmacy patterns in a given population over a 4-year period (2011-2015). A cross-sectional, observational study among the EpiChron Cohort, including anonymized demographic, clinical and drug dispensation information […]
  Sara Mucherino
• Influence of Active and Healthy Ageing on Quality of Life Changes: Insights from the Comparison of Three European Countries 30 abril 2021
  This study aimed to analyze the determinants of quality of life (QoL) in older people in three European countries (Portugal, Spain and Sweden). A sample of 7589 participants in waves 4 (2011) and 6 (2015) of the Survey on Health, Aging, and Retirement in Europe (SHARE) project, aged 50 and over and living in Portugal, […]
  Alba Ayala
• PD-L1 as a Prognostic Factor in Early-Stage Colon Carcinoma within the Immunohistochemical Molecular Subtype Classification 30 abril 2021
  CONCLUSIONS: Our study suggests that PD-L1 expression is an independent prognostic factor in patients with stage II/III colon cancer. Additionally, it successfully differentiates patients with better prognosis in the CMS2/CMS3 group and may prove significant for the clinical relevance of the CMS classification.
  Pablo Azcue
• Self-perceived health in Spanish and Portuguese young seniors after the great recession according to the European Health Survey: A cross-sectional study 27 abril 2021
  OBJECTIVE: The aim of this study is to describe self-perceived health (SPH) in Spanish and Portuguese population aged between 65 and 74years old and to analyze other associated factors measured in the European Health Interview Survey (EHIS) in 2014.
  Ana M Pereira-de-Sousa
• Validation into Spanish of the revised Patients' Attitudes Towards Deprescribing (rPATD) questionnaire to assess patients' attitudes towards deprescribing. Research protocol 24 abril 2021
  CONCLUSION: The use of the rPATD questionnaire, alone or integrated into other more complex interventions, may lead to an improvement in the quality of care for the polymedicated patients.
  José Ignacio de Juan-Roldán
• News articles in the spanish digital press media: characteristics of the sample and adherence to World Health Organization guidelines. 21 abril 2021
  CONCLUSIONS: Adherence to WHO recommendations is very low in suicide news articles. Furthermore, almost one third of them are avoidable. The identified profile points out the need for interventions aimed at the media. Besides, it allows adjusting their contents to the identified specific needs.
  Carlos J Rodríguez Rodríguez-Caro
• The Perspectives of Patients with Chronic Diseases and Their Caregivers on Self-Management Interventions: A Scoping Review of Reviews 19 abril 2021
  CONCLUSION: The process of SM shaped the perspectives of patients and their caregivers on SM interventions. Their perspectives were influenced by the perceived benefit of the intervention, the sense of community with peers, the intervention's usability, and the level of individualised care. Our findings can inform the selection of patient-important outcomes, decision-making processes, including the […]
  Ena Niño de Guzmán Quispe
• Nonadherence after hospital discharge in patients with schizophrenia or schizoaffective disorder: A six-month naturalistic follow-up study 19 abril 2021
  CONCLUSIONS: A large percentage of patients with schizophrenia or schizoaffective disorder did not adhere to their treatment in the post-discharge follow-up period. The profile identified may enable better prevention of this problem. Specific reasons for nonadherence should also be explored to provide individualized strategies.
  Dulcinea Vega